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In 1922, Henri and his nephews, the Chapuis, founded the Chapuis Comoy pipe factory in Saint-Claude, France, which shortly after began producing pipes bearing the partnered families names Cha for Chapuis, and Com for Comoy

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the synthetic nicotine case shows how important is for regulatory authorities to act in advance to new product and technologies and be a step ahead of companies, in order to ensure control over the market and avoid misregulation or no regulation areas.